Cameron Dezfulian, MD, Awarded a Grant from PPDC for Pediatric Development of Threadrite IV

Threadrite IV moved a step closer to reality in kids when Cameron Dezfulian, MD, was awarded a $50,000 grant for pediatric development of the product from the Philadelphia Pediatric Device Consortium (PPDC) on February 6, 2019. Threadrite IV is an assistive catheter guidance invention that improves success in catheterization reducing patient pain and hospital costs.


“Up to this point, our focus has been geared to using Pitt Coulter and PInCh funds for adult-size IV prototype development and testing to prove efficacy,” said Dr. Dezfulian, Associate Professor of Adult and Pediatric Critical Care Medicine, and Clinical and Translational Science. “This new funding opens up another patient population for us. We’ll be using the funds to overcome the technical challenges for Threadrite IV use in children as well as understanding the needs in this population.”


Dezfulian elaborated saying that the PPDC funding allows his team to advance the miniaturization of the catheter, perform testing simulating pediatric use, and to conduct a small pediatric study of IV use and problems.


Threadrite IV uses a modified standard IV catheter connected to a lightweight reusable detection unit, which measures electrical resistance and signals vessel entry instantly with a light, tone and vibration.


At the Pitt Innovation Challenge (PInCh) 2018 awards, the Threadrite IV team was one of three finalists to be awarded $100,000 for their invention. Previously ThreadRite IV has benefited from funding from the Center for Medical Innovation, the Chancellor’s Innovation Fund and the Coulter Program @ Pitt. ThreadRite IV was invented by a Pitt team led by Dr. Dezfulian and Dr. William “Buddy” Clark from the Department of Mechanical Engineering and Material Sciences.


Dr. Dezfulian’s research interests include neuroprotection after cardiac arrest using NO/nitrite, post-resuscitation critical care optimization, and phenotyping of injury patterns after out-of-hospital cardiac arrest. He is a scientist in the Safar Center for Resuscitation Research and Vascular Medicine Institute as well as a member of the UPMC Post-Cardiac Arrest Service.