Tamil S. Anthonymuthu, PhD

Research Assistant Professor of Critical Care Medicine

Contact Information

atamil[at]pitt.edu

Education & Training

B Tech, Chemical Engineering, University of Madras, 2001
M Tech, Biotechnology, Anna University, 2003
PhD, Anna University, 2008
Post Doctoral Research Fellow, Brigham Young University, 2012
Post Doctoral Research Fellow, University of Pittsburgh, 2013

Research, Clinical & Academic Interests

  • Lipidomics: Clinical Lipidomics, Redox lipidomics
  • Lipoproteomics
  • Role of lipid mediators in cell death


Anthonymuthu TS, Kenny EM, Shrivastava I, Tyurina YY, Hier ZE, Ting H-C, et al. Empowerment of 15-lipoxygenase catalytic competence in selective oxidation of membrane ETE-PE to ferroptotic death signals, HpETE-PE. Journal of the American Chemical Society. 2018;140(51):17835-9.

Anthonymuthu TS, Kenny EM, Lamade AM, Gidwani H, Krehel NM, Misse A, et al. Lipidomics detection of brain Cardiolipins in plasma is associated with outcome after cardiac arrest. Critical care medicine. 2019;47(4):e292-e300.

Anthonymuthu TS, Kenny EM, Amoscato AA, Lewis J, Kochanek PM, Kagan VE, et al. Global assessment of oxidized free fatty acids in brain reveals an enzymatic predominance to oxidative signaling after trauma. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease. 2017;1863(10):2601-13.

Wenzel SE, Tyurina YY, Zhao J, Croix CMS, Dar HH, Mao G, Tyurin VA, Anthonymuthu TS, et al. PEBP1 wardens ferroptosis by enabling lipoxygenase generation of lipid death signals. Cell. 2017;171(3):628-41. e26.