Christopher Seymour, MD, MSc, Appointed to the International Sepsis Forum Council; Joins Department Chair Derek Angus

Associate Professor Christopher Seymour, MD, MSc, was appointed a council member of the International Sepsis Forum (ISF) on March 1, 2018. ISF is an international collaboration formed to reduce the global burden of morbidity and mortality from sepsis. Dr. Seymour joins 17 other prominent international academics and sepsis opinion leaders on the ISF Council, which meets twice a year. The Council focuses exclusively on improving the management of sepsis and septic shock by developing an international consensus on the latest understanding of key scientific and clinical issues, and disseminating emerging practice guidelines to researchers, intensivists, and other critical care professionals worldwide. The Department of Critical Care Medicine (CCM) at the University of Pittsburgh now has two faculty members on the Council simultaneously. Dr. Seymour joins CCM Chair, Professor Derek Angus, MD, MPH, who is the ISF Secretary and Immediate Past Chair.

"It is a huge honor to be invited to join the prestigious ISF Council," said Dr. Seymour of his appointment. "The fact that our Department has two sitting council members is a significant sign of the respect we have achieved for the scope and caliber of sepsis research undertaken at Pitt."

Dr. Seymour studies new methods for beginning sepsis treatment earlier. He has fostered the growth of a new field: prehospital sepsis. By identifying important but under-appreciated epidemiology and public health burdens for sepsis, his research has led to new international criteria for sepsis as well as innovative ways to find and treat sepsis in the emergency department. His work will lead to improved sepsis outcomes, the underlying goal of the International Sepsis Forum.

An internationally recognized researcher of critical illness, Dr. Angus conducts clinical, epidemiologic and translational studies of sepsis, pneumonia, and multisystem organ failure and health services research of the organization and delivery of critical care services. He has led several large NIH-funded multicenter studies in the critically ill, the most recent of which is ProCESS (Protocolized Care for Early Septic Shock), a 40-center study focusing on how to best provide early resuscitation for septic shock.

Both Dr. Seymour and Dr. Angus conduct their research within the Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Center of the Department of Critical Care Medicine. Sepsis and septic shock is one of six key research foci of CRISMA.

ISF was founded in 1997 to improve the care of critically care patients with sepsis by:

  • Promoting an improved understanding of the basic biology and pathology of sepsis
  • Enhancing the understanding of the epidemiology of sepsis
  • Improving the design and conduct of clinical research to improve the management of septic patients
  • Educating health professionals in the optimal management of patients with sepsis
  • Raising the profile of sepsis as a global health challenge with the public, with healthcare practitioners, with industry, and with global health agencies