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Regulation of the heat shock response by a nuclear protein called Poly (ADP) ribose polymerase (PARP); use of plasma exchange in multi-organ failure associated with sepsis.
Dr. Angus is Professor and Chair of the Department of Critical Care Medicine and Director of CRISMA (Clinical Research, Investigation, and Systems Modeling of Acute Illnesses) Center at the University of Pittsburgh.
Dr. Bell's work focuses on developing a better understanding, and ultimately better treatments, for children with critical neurological injuries.
Dr. Carcillo's research career has been devoted to developing clinical practices which improve outcomes in children with Sepsis.
Dr. Chou's research focuses on the use of human molecular biomarkers to probe mechanisms and predict outcomes in acute brain injury conditions such as subarachnoid hemorrhage (SAH) and hypoxic ischemic brain injury from cardiac arrest.
Exploring the intersection of advanced quantitative methods and bedside care with the ultimate vision of leveraging mathematical, computational and engineering expertise to deliver improved personalized care to the critically ill.
Dr. Dezfulian is interested in ways of reducing cerebral and cardiac injury resulting from cardiac arrest.