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The role of glycocalyx shedding and platelet adhesion in sepsis-induced microvascular dysfunction

PI: Hernando Gomez, MD, MPH

Funding Info: Vascular Medicine Institute. (The Vascular Medicine Institute is a part of the University of Pittsburgh School of Medicine’s Department of Medicine, and is supported by the Hemophilia Center of Western Pennsylvania and the Institute for Transfusion Medicine.)

This project is investigating the potential role of denudation of the gloycocalyx, microvascular dysfunction, and platelet adhesion in the development of sepsis-induced acute kidney injury (AKI). The project employs multiple aims and innovative imaging modalities, and will set the stage for an external grant application.

The Vascular Medicine Institute is a part of the University of Pittsburgh School of Medicine’s Department of Medicine, and is supported by the Hemophilia Center of Western Pennsylvania and the Institute for Transfusion Medicine.