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David T. Huang, MD, MPH, FACEP, FCCM

Associate Professor, Departments of Critical Care Medicine, Emergency Medicine, and Clinical and Translational Science

Director, Multidisciplinary Acute Care Research Organization (MACRO)

Administrative Core Director, CRISMA Center

Associate Medical Director, Transplant Intensive Care Unit, UPMC Montefiore

Admin Assistant: Meghan Buck
Dr. Huang trained in Emergency Medicine at Henry Ford Hospital, followed by a CCM Fellowship, NIH Research Fellowship, and MPH at the University of Pittsburgh. He is currently (Jan 2017) an Associate Professor of Critical Care Medicine, Emergency Medicine, and Clinical and Translational Science at the University of Pittsburgh. His research focuses on multicenter clinical trials that span the ED and ICU. He served as Medical Monitor of the ProCESS trial, and is currently PI of the ProACT trial (1R01GM101197;, and a leader of the ROSE trial (

Dr. Huang is a Fellow of the American College of Emergency Physicians and the American College of Critical Care Medicine. He is Director of MACRO (Multidisciplinary Acute Care Research Organization), Director of the CRISMA Center Administrative and Long-Term Follow-up Cores, and Associate Director of the Abdominal Organ Transplant ICU.


See David T. Huang's Investigator page

Current Research Projects

ProACT – Procalcitonin Antibiotic Consensus Trial

ProCESS – Protocolized Care for Early Septic Shock

Completed Research

The following refereed articles were generated primarily from completed research projects.

Huang DT, Osborn TM, Gunnerson KJ, Gunn SR, Trzeciak S, Kimball E, Fink MP, Angus DC, Dellinger RP, Rivers EP; Society of Critical Care Medicine; American College of Emergency Physicians; Society of Academic Emergency Medicine; Council of Emergency Medicine Residency Directors; Emergency Medicine Residents Association.  Critical care medicine training and certification for emergency physicians.  Crit Care Med. 2005 Sep;33:2104-09.

Huang DT, Osborn T, Gunnerson K, Gunn S, Trzeciak S, Kimball E, Fink MP, Angus DC, Dellinger RP, Rivers EP. Critical care medicine training and certification for emergency physicians.  Ann Emerg Med. 2005; 46:217-23.

Huang DT, Clermont G, Sexton JB, Karlo CA, Miller RG, Weissfeld LA, Rowan KM, Angus DC.  Perceptions of safety culture vary across the intensive care units of a single institution.  Crit Care Med. 2007 Jan;35:165-76.

Pham JC, Huang DT, McGeorge FT, Rivers EP.  Clarification of cyanide's effect on oxygen transport characteristics in a canine model.  Emerg Med J. 2007;24:152-6. PMC2816935

Huang DT, Clermont G, Dremsizov TT, Angus DC.  Implementation of early goal-directed therapy for severe sepsis and septic shock: A decision analysis.  Crit Care Med. 2007 Sep;35:2090-100.

Delaney A, Angus DC, Bellomo R, Cameron P, Cooper DJ, Finfer S, Harrison DA, Huang DT, Myburgh JA, Peake SL, Reade MC, Webb SA, Yealy DM; Resuscitation in Sepsis Evaluation (ARISE); Protocolized Care for Early Septic Shock (ProCESS) Investigators; Protocolised Management In Sepsis (ProMISe) Investigators.  Bench-to-bedside review: the evaluation of complex interventions in critical care.  Crit Care. 2008;12:210.

Huang DT, Weissfeld LA, Kellum JA, Yealy DM, Kong L, Martino M, Angus DC; GenIMS Investigators.  Risk prediction with procalcitonin and clinical rules in community-acquired pneumonia.  Ann Emerg Med. 2008 Jul; 52:48-58.e2.

Huang DT, Angus DC, Kellum JA, Pugh NA, Weissfeld LA, Struck J, Delude RL, Rosengart MR, Yealy DM.  Midregional proadrenomedullin as a prognostic tool in community-acquired pneumonia.  CHEST. 2009 Sep;136:823-31.

Mayglothling JA, Gunnerson KJ, Huang DT.  Current practice, demographics and trends of critical care trained emergency physicians in the United States.  Acad Emerg Med. 2010 Mar;17:325-9.

Patterson PD, Huang DT, Fairbanks RJ, Wang HE.  The emergency medical services safety attitudes questionnaire.  Am J Med Qual. 2010 Mar-Apr;25(2):109-15.

Reade MC, Huang DT, Bell D, Coats TJ, Cross AM, Moran JL, Peake SL, Singer M, Yealy DM, Angus DC; British Association for Emergency Medicine; UK Intensive Care Society; UK Society for Acute Medicine; Australasian Resuscitation in Sepsis Evaluation Investigators; Protocolized Care for Early Septic Shock Investigators.  Variability in management of early severe sepsis.  Emerg Med J. 2010 Feb;27:110-5.

Huang DT, Clermont G, Kong L, Weissfeld LA, Sexton JB, Rowan KM, Angus DC.  Intensive care unit safety culture and outcomes: a US multicenter study.  Int J Qual Health Care. 2010 Apr 9;22:151-61.

Patterson PD, Huang DT, Fairbanks RJ, Simeone S, Weaver M, Wang HE. Variation in emergency medical services workplace safety culture.  Prehospital Emergency Care 2010;14:1-13.

Yende S, van der Poll T, Lee M, Huang DT, Newman AB, Kong L, Kellum JA, Harris TB, Bauer D, Satterfield S, Angus DC; for the GenIMS and Health ABC study.  The influence of pre-existing diabetes mellitus on the host immune response and outcome of pneumonia: analysis of two multicentre cohort studies.  Thorax. 2010 Oct;65(10):870-7.

Al-Khafaji A, Huang DT.  Critical care management of patients with end-stage liver disease.  Crit Care Med. 2011; 2011 Feb 17.